MRCS Knowledge: Achalasia

Ach

Today’s MRCS Core Knowledge focuses on Achalasia

Background

Achalasia is the absence of oesophageal peristalsis and failure of relaxation of the lower oesophageal sphincter (LOS) due to degeneration of the myenteric plexus

Aetiology

Peaks in young adulthood and elderly

Signs and Symptoms

Slowly progressive dysphagia, liquids >solids, regurgitation as disease progresses, weight loss, aspiration, chest pain

Investigations

Barium swallow: has classic ‘birds beak’ appearance with a tapered distal oesophagus and dilated mega oesophagus proximal to the constriction
OGD: exclude benign/malignant strictures
Oesophageal manometry: abnormally high lower oesophageal sphincter pressures

Management

Endoscopic: balloon dilatation, botox injections
Surgical: Heller’s myotomy open or laparoscopic

Prognosis

Balloon dilatation is successful in 80%
Complications include: aspiration pneumonia and malignant change in distal oesophagus

Further Info:
For further info and commonly asked questions on achalasia be sure to sign up to the Question Bank.

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